In July 1941, following the outbreak of the Soviet-German War, the Romanian army occupied Bessarabia, and the Jewish community of Telenești was decimated. On July 18, when the Romanian authorities arrived in the town, some 300 Jews (almost all of them women and children) were shot in the courtyard of the local resident Itta Shteimann. Apparently in the same month, 150 Jewish men from Teleneşti were shot in a ravine near the village of Budǎi. Later, some Jews, both individuals and families, who had been caught hiding in the town and its vicinity were shot outside Telenești, near the household of Filipp Kasirov.
Telenești was liberated by the Red Army in April 1944.