In 1939 Burlatskoye village and Burlatskoye County were part of the Ordzhonikidze Kray District, which before the Revolution of 1917 was outside of the tsarist Pale of Settlement. No Jews lived in this area until the beginning of the Soviet-German War. However, with the German invasion of the USSR on June 22, 1941, Ordzhonikidze Kray District became a destination of civilian evacuation or flight, including of many Jews from Soviet Ukraine, Bessarabia (today Moldova) and Belorussia. With the summer offensive of the German army at the end of June 1942, the Germans began to invade the Northern Caucasus. The Wehrmacht occupied Burlatskoye between the middle and end of August 1942. Two murder operations were carried out near Burlatskoye - on September 5 and on October 15, 1942. Two Jewish women and members of a Jewish family were killed by the local police forces under German supervision. The September murder was carried out in the village of Spasskoye, probably at the animal burial ground; the second murder took place at the prison in the village of Sotnikovskaya.
The Red Army liberated Burlatskoye on January 11, 1943.